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Both hesperidin and pinocembrin activate the Nrf2 pathway, showing therapeutic potential in intervertebral disc degeneration models (Zhu J

doi: 10.1111/acel.14064, 33

Coupled steady-state kinetic measurements with GSSR and GSH revealed that both half-reactions usually occur with second order rate constants around 10 5 to 10 6 M 1 s 1 with the reductive half-reaction being slower for wild-type glutaredoxins 11,14,15,17,19

reads were trimmed using TrimGalore (48) and aligned to Ensemble hg38 using STAR (49)

To assess whether incorporating a second variable (ferroptosis genes) into the univariate model with EZH2 improved the models fit, we performed likelihood-ratio tests